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Search Results for " epithelial cancer "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T41286	N6-Isopentenyladenosine		Endogenous Metabolite , Autophagy
	N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different...		Endogenous Metabolite , Autophagy
T0459	Sulindac	Arthrocine,MK-231,Clinoril,Sulindac sulfoxide	COX , Autophagy
	Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...		COX , Autophagy
T4102	Goserelin acetate	Fertilan,ICI-118630 acetate,Zoladex	Apoptosis , GNRH Receptor
	Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.		Apoptosis , GNRH Receptor
T17216	Valspodar	PSC 833	P-gp
	Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a chemical sensitizer to study advanced epithelial ovarian cancer.		P-gp
T24997	ABT-510 acetate	ABT 510 acetate	Apoptosis
	ABT-510 acetate is an endogenous anti-angiogenic TSP peptide inhibitor, a thrombospondin analog, with anti-inflammatory, anti-cancer and anti-angiogenic activity that induces apoptosis and inhibits ovarian tumor growth i...		Apoptosis
T77701	FL118	FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin	Survivin
	FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin s...		Survivin
TP1565L1	Foxy-5 Ammonium Salt	Foxy-5 Ammonium Salt（881188-51-8 Free base)	Wnt/beta-catenin
	Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in...		Wnt/beta-catenin
T73300	AXL-IN-13		FLT , TAM Receptor , PDGFR , TGF-beta/Smad
	AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 value of 1.6 nM and a Kd value of 0.26 nM.AXL-IN-13 exhibits anticancer activity, reverses TGF-β1-induced epithelial-mesenchymal transition (EMT) and inh...		FLT , TAM Receptor , PDGFR , TGF-beta/Smad
T11793	KY-05009		Wnt/beta-catenin
	KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity o...		Wnt/beta-catenin
T19710	Ciglitazone	Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878	Apoptosis , p38 MAPK , PPAR
	Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelia...		Apoptosis , p38 MAPK , PPAR
T38752	EW-7195		ALK , TGF-beta/Smad
	EW-7195 is a selective and potent inhibitor of ALK5 (TGFβR1) with an IC50 value of 4.83 nM.EW-7195 has an affinity for ALK5 that is more than 300-fold higher than that of p38α.EW-7195 has an inhibitory effect on TGF-β1-i...		ALK , TGF-beta/Smad
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
T28899	T-1840383
	T-1840383 is an inhibitor of VEGF-induced VEGFR-2 phosphorylation and HGF-induced c-Met phosphorylation in vascular endothelial cells and cancer epithelial cells.
T79789	DT-6		TGF-beta/Smad
	DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing potential for cancer research applications [1].		TGF-beta/Smad
T83076	Anticancer agent 93
	Anticancer Agent 93, a 4-Hydroxycoumarin derivative, inhibits the invasion and migration of lung cancer cells through modulation of epithelial-mesenchymal transition (EMT) effector expression [1].
T81850	MASTL-IN-2
	MASTL-IN-2 is a potent inhibitor of microtubule-associated serine/threonine kinase-like (MASTL). It demonstrates notable efficacy in suppressing the proliferation of human epithelial MIA PaCa cancer cells, exhibiting an ...
TP1296	Foxy-5 TFA(881188-51-8 free base)	Foxy-5 (TFA)
	Foxy-5 is a peptide that mimics the WNT5A protein and is expected to reduce the mobility of the cancer cells. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the mig...
T70223	UA8967
	UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 12...
T83075	Anticancer agent 94
	Anticancer agent 94, a 4-Hydroxycoumarin derivative, inhibits lung cancer cell invasion and migration by modulating the expression of epithelial-mesenchymal transition (EMT) effectors [1].
T76994	Sotevtamab
	Sotevtamab (16B5), a humanized IgG2 monoclonal antibody (mAb) targeting clusterin, acts as an inhibitor of the epithelial to mesenchymal transition, making it a valuable agent for cancer research [1] [2] [3].
T36860	C22 Sphingomyelin (d18:1/22:0)	C22 Sphingomyelin (d18:1/22:0)
	C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel...
T63827	HSP90-IN-10
	HSP90-IN-10 is a potent inhibitor of HSP90. HSP90-IN-10 exhibits potent anti-proliferative effects on HCC1954 breast cancer cells (IC50: 6 μM). hSP90-IN-10 induces apoptosis without inhibiting the growth of normal epithe...
T61815	AL-GDa62
	AL-GDa62, a potential synthetic lethal agent for gastric cancer treatment, demonstrates efficacy with EC50 values of 3.2 μM in MCF10A-WT (wild-type) isogenic mammary epithelial cells and 2 μM in MCF10A-CDH1 -/- cells [1]...
T63325	ATX inhibitor 9
	ATX inhibitor 9 is a thickened heteroaryl derivative compound and a potent inhibitor of ATX. Among them Autotaxin (ATX), also known as ENPP2, is a secreted enzyme highly expressed mainly in lung cancer cells, bronchial e...
TP1565L	Foxy-5 acetate	Foxy-5 acetate(881188-51-8 free base)	Wnt/beta-catenin
			Wnt/beta-catenin
T78307	Catumaxomab
	Catumaxomab, a trifunctional IgG2 antibody with mouse and rat heavy and light chain components, targets human EpCAM and CD3 receptors. Its Fc region exhibits affinity for FcγRI (CD64), FcγRIIA (CD32a), and FcγRIII (CD16)...
T75941	Foxy-5 TFA
	Foxy-5 TFA, a WNT5A agonist and mimicking peptide of WNT5A (a non-canonical Wnt family member), induces cytosolic free calcium signaling without altering β-catenin activation. This compound inhibits the migration and inv...
T36460	CAY10736	CAY10736
	CAY10736 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.827-9.89 μM). CAY10736 inhibits migration and epithelial-to-mesenchymal ...
T36846	Chromomycin A2
	Chromomycin A2 is an aureolic acid that has been found in several marine actinomycetes and has antibacterial and anticancer activities. Chromomycin A2 inhibits the growth of B. subtilis in an agar diffusion assay. It als...
T62822	CT1-3
	CT1-3 is a potent anti-cancer agent. CT1-3 regulates the JNK/Bcl-2/Bax/XIAP pathway, which induces mitochondria-mediated apoptosis. CT1-3 regulates the E-cadherin/Snail axis to inhibit epithelial mesenchymal transition (...
TP2128	R8-T198wt
	Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1 and Bad; induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. Also inhibits Pim...
T36497	CAY10735	CAY10735
	CAY10735 is an anticancer compound.1 It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56 μM). CAY10735 inhibits migration of and the epithelial-to-mese...
T63768	Antitumor agent-78
	Antitumor agent-78 inhibits GPx-4 and elevates COX2, leading to ferroptosis. antitumor agent-78 activates the tumor cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and inhibits the epithelial mesenchymal transitio...
T37564	C4 Ceramide (d18:1/4:0)	C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)
	C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used...
T61585	Sulindac sodium
	Sulindac (sodium) (MK-231) is an orally active nonsteroidal anti-inflammatory agent. Sulindac (sodium) is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthr...
T62814	Antitumor agent-77
	Antitumor agent-77 inhibits the growth and migration of cancer cells and has anticancer effects. antitumor agent-77 inhibits GPx-4 and enhances COX2-induced iron sagging. antitumor agent-77 activates the intrinsic apopto...
T83765	Dendrogenin A	DDA
	Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest...
T65994	(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
	Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a ...

Compounds

N6-Isopentenyladenosine

T41286

Synonym:

Target: Endogenous Metabolite, Autophagy

Sulindac

T0459

Synonym: Arthrocine,MK-231,Clinoril,Sulindac sulfoxide

Target: COX, Autophagy

Goserelin acetate

T4102

Synonym: Fertilan,ICI-118630 acetate,Zoladex

Target: Apoptosis, GNRH Receptor

Synonym: ABT 510 acetate

Target: Apoptosis

FL118

T77701

Synonym: FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin

Target: Survivin

Foxy-5 Ammonium Salt

TP1565L1

Synonym: Foxy-5 Ammonium Salt（881188-51-8 Free base)

Target: Wnt/beta-catenin

AXL-IN-13

T73300

Synonym:

Target: FLT, TAM Receptor, PDGFR, TGF-beta/Smad

KY-05009

T11793

Synonym:

Target: Wnt/beta-catenin

Ciglitazone

T19710

Synonym: Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878

Target: Apoptosis, p38 MAPK, PPAR

EW-7195

T38752

Synonym:

Target: ALK, TGF-beta/Smad

Target: TGF-beta/Smad

Foxy-5 TFA(881188-51-8 free base)

TP1296

Synonym: Foxy-5 (TFA)

C22 Sphingomyelin (d18:1/22:0)

T36860

Synonym: C22 Sphingomyelin (d18:1/22:0)

Synonym: Foxy-5 acetate(881188-51-8 free base)

Target: Wnt/beta-catenin

C4 Ceramide (d18:1/4:0)

T37564

Synonym: C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0)

(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

T65994

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T3862	Irigenin		NF-κB , Integrin
	Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...		NF-κB , Integrin
T4S0969	Obtusifolin		Antioxidant , NF-κB
	1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...		Antioxidant , NF-κB
T5S1882	Songorine	Napellonine,Zongorine,Bullatine G	Others , GABA Receptor
	Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.		Others , GABA Receptor
T7982	3,6-Dihydroxyflavone		Others
	3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.		Others
TN1433	Batatasin III		FAK , Others , Akt
	Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancer activities. Batatasin III has a long-term inhibitory effect on whole-...		FAK , Others , Akt
T4869	D-Allose	β-D-Allopyranose,D-(+)-ALLOSE	Others , Endogenous Metabolite
	D-Allose (β-D-Allopyranose) is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refractory prostate cancer ...		Others , Endogenous Metabolite
T3123	Allicin		ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection
	Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus...
T35749	Thymohydroquinone	Thymoquinol	Antioxidant , Reactive Oxygen Species
	Thymohydroquinone (Thymoquinol) is a monoterpenoid phenolic compound found in thyme, oregano, and other plants in the labiaceae family. Thymohydroquinone inhibits cancer cell growth, reduces oxidative stress and modulate...		Antioxidant , Reactive Oxygen Species
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....

天然物製品

Irigenin

T3862

Synonym:

Target: NF-κB, Integrin

Obtusifolin

T4S0969

Synonym:

Target: Antioxidant, NF-κB

Songorine

T5S1882

Synonym: Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Target: FAK, Others, Akt

D-Allose

T4869

Synonym: β-D-Allopyranose,D-(+)-ALLOSE

Target: Others, Endogenous Metabolite

Allicin

T3123

Synonym:

Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection

Thymohydroquinone

T35749

Synonym: Thymoquinol

Target: Antioxidant, Reactive Oxygen Species

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-00155	Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated	Human	HEK293 Cells
	Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also ...
TMPY-02258	Kallikrein 3/KLK3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that i...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPK-00865	TM4SF1 Protein-VLP, Human, Recombinant	Human	HEK293 Cells
	Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial can...
TMPK-00710	Claudin-4 Protein-VLP, Human, Recombinant	Human	HEK293 Cells
	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been asso...
TMPY-03979	ARHI Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	ARHI, also known as DIRAS3, belongs to the small GTPase superfamily, Di-Ras family. ARHI gene is a novel tumor suppressor gene located on chromosome 1p31. Downregulation of ARHI expression has been detected in many types...
TMPK-00055	IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling response...
TMPK-01299	CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)	Cynomolgus	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at meta...
TMPY-00519	Gastrokine 1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in...
TMPK-00898	EphB3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Although EphB3 expression is down-regulated in colorectal cancer (CRC) cells compared with normal intestinal epithelial cells.EphB3 is down-regulated in CRC compared to normal mucosa. Hypermethylation of CpG island is co...
TMPK-00224	BTN3A2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	BTN3A2/BT3.2 butyrophilin mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).In conclusion, BT3.2 protein is a pote...
TMPY-04828	TFF3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types ...
TMPY-02760	CALML3 Protein, Human, Recombinant (His)	Human	E. coli
	Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ...
TMPY-04133	UNC5B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-00507	UNC5B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-04003	UNC5B Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPK-01137	FAM3D Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m...
TMPK-00026	IL-9 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl...
TMPK-00568	IL-9 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl...
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated	Human	HEK293 Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which un...
TMPY-04899	OGN/Osteoglycin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protei...
TMPY-04203	RAB1B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPK-00025	IL-9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pl...
TMPJ-01432	CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated	Human	HEK293 Cells
	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by t...
TMPY-02023	CD46 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white bloo...
TMPY-01583	ALDH1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has be...
TMPH-03753	MYLK Protein, Human, Recombinant (His)	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...
TMPY-03172	Argininosuccinate lyase Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established r...
TMPJ-01089	TFF1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing...
TMPY-00585	Annexin A8 Protein, Human, Recombinant (His)	Human	E. coli
	We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA...
TMPJ-00698	BTNL2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domai...
TMPJ-00785	FABP3 Protein, Human, Recombinant (His)	Human	E. coli
	Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in...
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...
TMPY-01890	CLIC4 Protein, Human, Recombinant (His)	Human	E. coli
	Chloride intracellular channel protein 4, also known as Intracellular chloride ion channel protein p64H1 and CLIC4, is a member of the chloride channel CLIC family. It contains oneGST C-terminal domain. CLIC4 is a mem...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and t...
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...

Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated

TMPJ-00155

Species: Human

Expression System: HEK293 Cells

Kallikrein 3/KLK3 Protein, Human, Recombinant (His)

TMPY-02258

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

TM4SF1 Protein-VLP, Human, Recombinant

TMPK-00865

Species: Human

Expression System: HEK293 Cells

Claudin-4 Protein-VLP, Human, Recombinant

TMPK-00710

Species: Human

Expression System: HEK293 Cells

ARHI Protein, Human, Recombinant (mFc)

TMPY-03979

Species: Human

Expression System: HEK293 Cells

IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00055

Species: Human

Expression System: HEK293 Cells

CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)

TMPK-01299

Species: Cynomolgus

Expression System: HEK293 Cells

Gastrokine 1 Protein, Human, Recombinant (His)

TMPY-00519

Species: Human

Expression System: Baculovirus Insect Cells

EphB3 Protein, Human, Recombinant (His)

TMPK-00898

Species: Human

Expression System: HEK293 Cells

BTN3A2 Protein, Human, Recombinant (His & Avi)

TMPK-00224

Species: Human

Expression System: HEK293 Cells

TFF3 Protein, Human, Recombinant (His)

TMPY-04828

Species: Human

Expression System: HEK293 Cells

CALML3 Protein, Human, Recombinant (His)

TMPY-02760

Species: Human

Expression System: E. coli

UNC5B Protein, Human, Recombinant (His)

TMPY-04133

Species: Human

Expression System: HEK293 Cells

UNC5B Protein, Human, Recombinant (hFc)

TMPY-00507

Species: Human

Expression System: HEK293 Cells

UNC5B Protein, Rat, Recombinant (hFc)

TMPY-04003

Species: Rat

Expression System: HEK293 Cells

FAM3D Protein, Human, Recombinant (hFc)

TMPK-01137

Species: Human

Expression System: HEK293 Cells

IL-9 Protein, Mouse, Recombinant (hFc)

TMPK-00026

Species: Mouse

Expression System: HEK293 Cells

IL-9 Protein, Cynomolgus, Recombinant (His)

TMPK-00568

Species: Cynomolgus

Expression System: HEK293 Cells

HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated

TMPJ-00415

Species: Human

Expression System: HEK293 Cells

OGN/Osteoglycin Protein, Human, Recombinant (His)

TMPY-04899

Species: Human

Expression System: HEK293 Cells

RAB1B Protein, Human, Recombinant (hFc)

TMPY-04203

Species: Human

Expression System: HEK293 Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

TMPY-01033

Species: Human

Expression System: HEK293 Cells

IL-9 Protein, Human, Recombinant (hFc)

TMPK-00025

Species: Human

Expression System: HEK293 Cells

CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated

TMPJ-01432

Species: Human

Expression System: HEK293 Cells

CD46 Protein, Human, Recombinant (His)

TMPY-02023

Species: Human

Expression System: HEK293 Cells

ALDH1A1 Protein, Human, Recombinant (His)

TMPY-01583

Species: Human

Expression System: E. coli

MYLK Protein, Human, Recombinant (His)

TMPH-03753

Species: Human

Expression System: E. coli

Argininosuccinate lyase Protein, Human, Recombinant (His & GST)

TMPY-03172

Species: Human

Expression System: Baculovirus Insect Cells

TFF1 Protein, Mouse, Recombinant (His)

TMPJ-01089

Species: Mouse

Expression System: HEK293 Cells

Annexin A8 Protein, Human, Recombinant (His)

TMPY-00585

Species: Human

Expression System: E. coli

BTNL2 Protein, Mouse, Recombinant (His)

TMPJ-00698

Species: Mouse

Expression System: HEK293 Cells

FABP3 Protein, Human, Recombinant (His)

TMPJ-00785

Species: Human

Expression System: E. coli

ALDH3A1 Protein, Human, Recombinant (His)

TMPY-02299

Species: Human

Expression System: Baculovirus Insect Cells

CLIC4 Protein, Human, Recombinant (His)

TMPY-01890

Species: Human

Expression System: E. coli

Cathepsin V Protein, Human, Recombinant (His)

TMPY-01249

Species: Human

Expression System: HEK293 Cells

Artemin Protein, Mouse, Recombinant (hFc)

TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

カタログ番号	製品名
L2195	Anti-Prostate Cancer Compound Library		2070 compounds
	2070 compounds associated with prostate cancer that can be used for high-throughput and high-content screening.

ライブラリー

Anti-Prostate Cancer Compound Library

L2195

Compounds: 2070